The German Football Association (DFB) confirmed Süle’s positive test on arrival at their national team’s headquarters.

Tim Meyer, Germany’s team doctor, said four other players were considered close contacts of Süle which required them to leave the training camp.

Four other players who were part of a nine-man group that travelled to the camp will remain but will distance themselves from the remainder of the squad.

Bayer Leverkusen defender Jonathan Tah, Wolfsburg’s Ridle Baku and Maximilian Arnold and Monaco's Kevin Volland were added to the German squad for the World Cup qualifiers.

"We’ve said that we want to keep acting responsibly and testing every player and staff member before they arrived," said Oliver Bierhoff, DFB director of national teams and academies.

"That is first done through a pool test.

"Prof Dr Meyer then told us that a pool test of one group of six was positive.

"The result of the following individual tests was that Niklas Süle was the one who tested positive.

"Tim Meyer’s work with the Health Department came out with the result this morning that Niklas Süle and four other players, Joshua Kimmich, Serge Gnabry, Karim Adeyemi and Jamal Musiala, must return home, with the other four of their nine-man travel group distancing from the rest of the group but not going home.

"We had to expect it – we know what can happen at times like these, and now we have to accept it and work our way around it.

"The upshot is that some players have been called up late.

"We want to concentrate on the game from this afternoon."

The DFB confirmed Süle is double-vaccinated and asymptomatic.

Kimmich, who has been forced to leave the camp, has come under the spotlight in Germany after recently confirming he is unvaccinated.

The 26-year-old has claimed he is concerned by the "lack of long-term studies", but said there was a "very good chance" he would get vaccinated.

Germany manager Hansi Flick has called for unvaccinated players not to be judged but said his view was that people should be vaccinated against COVID-19.

"We’re responsible to ensure that we all stay healthy, but no one is forced to get vaccinated," said Flick.

"We mustn’t judge those who haven’t been vaccinated because they have concerns about it.

"But my viewpoint is that we should all get the jab so we can come out the other side of this pandemic.

"We’re all role models and so have an even greater responsibility to set an example.

"I want all of my players to be vaccinated, but at the end of the day, it’s their decision.

"I hope things change so that we don’t have another incident where we have to send five players home.

"We need to see how we can best protect ourselves."

Germany has already qualified for the Qatar 2022 FIFA World Cup with two qualification matches remaining.

The German team have won seven of their eight qualifiers to book their place at the tournament, despite a shock loss to North Macedonia.

Germany face winless Liechtenstein today, before their final qualifier against Armenia on Sunday (November 14).

The German Football League recently revealed over 90 per cent of footballers in the country have been vaccinated against COVID-19.